Study: Damaged liver cells undergo reprogramming to regenerate

Biochemistry professor Auinash Kalsotra, second from left, and his team, including, from left, graduate students Waqar Arif, Joseph Seimetz and Sushant Bangru, uncovered the molecular underpinnings of liver regeneration. Photo by L. Brian Stauffer

Editor’s notes:
To reach Auinash Kalsotra, call 217-300-7654; email kalsotra@illinois.edu.

The paper “Alternative splicing rewires Hippo signaling pathway in hepatocytes to promote liver regeneration” is available online and from the U. of I. News Bureau.

Source: Illinois NEWS BUREAU

Summary
Study: Damaged liver cells undergo reprogramming to regenerate
Article Name
Study: Damaged liver cells undergo reprogramming to regenerate
Description
CHAMPAIGN, Ill. — In Greek mythology, Zeus punishes the trickster Prometheus by chaining him to a rock and sending an eagle to eat a portion of his liver every day, in perpetuity. It was the right organ to target – the liver has the ability to regenerate itself, though not overnight nor for eternity.